Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | RECQL | P46063 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | BLM | P54132 | 3/20 | 0.44 |
| ▸ | RGS12 | O14924 | 2/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478479 | 0.86 | ALDH1A1 (0.47) | LMNASMN1; SMN2MAPTALDH1A1GAA | |
| SCHEMBL28450866 | 0.85 | LMNA (0.60) | LMNASMN1; SMN2MAPTALDH1A1GAA | |
| SCHEMBL8479109 | 0.81 | MAPT (0.46) | LMNASMN1; SMN2MAPTALDH1A1GAA | |
| SCHEMBL4661446 | 0.80 | LMNA (0.61) | LMNASMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL4661444 | 0.80 | LMNA (0.61) | LMNASMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL32687981 | 0.78 | ALDH1A1 (0.45) | LMNASMN1; SMN2MAPTALDH1A1GAA | |
| SCHEMBL3368306 | 0.77 | TRPA1 (0.55) | LMNASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL32688380 | 0.74 | ALDH1A1 (0.48) | LMNAMAPTALDH1A1GAAHTT | |
| SCHEMBL11669632 | 0.72 | SMN1; SMN2 (0.60) | LMNASMN1; SMN2MAPTALDH1A1ATM | |
| SCHEMBL8544302 | 0.72 | SMN1; SMN2 (0.60) | LMNASMN1; SMN2MAPTALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996033179-A1 | THIOAMIDES DERIVATES AND THEIR USE AS INHIBITORS OF HYPER-PROLIFERATIVE CELL GROWTH | SUGEN, INC. (US) | 1996-10-24 | — | — | WO | disclosed |