Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBX7 | O95931 | 6/20 | 0.51 |
| ▸ | CDYL2 | Q8N8U2 | 6/20 | 0.51 |
| ▸ | CDYL | Q9Y232 | 6/20 | 0.51 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232260 | 0.83 | HSD17B10 (0.45) | MAPTLMNAPOLB | |
| SCHEMBL9231790 | 0.83 | LMNA (0.45) | KMT2AMAPTLMNAMEN1POLB | |
| SCHEMBL9234495 | 0.83 | LMNA (0.48) | MAPTLMNAPOLB | |
| SCHEMBL8669435 | 0.82 | HSD17B10 (0.54) | LMNAPOLB | |
| SCHEMBL9233268 | 0.80 | LMNA (0.43) | KMT2AALDH1A1LMNAMEN1POLB | |
| SCHEMBL9229586 | 0.79 | LMNA (0.53) | KMT2AMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL9234818 | 0.79 | LMNA (0.52) | KMT2AMAPTLMNAPOLB | |
| SCHEMBL9228514 | 0.78 | POLB (0.47) | MAPTPTGESALDH1A1LMNAPOLB | |
| SCHEMBL9573425 | 0.77 | SMN1; SMN2 (0.46) | MAPTALDH1A1LMNAPOLB | |
| SCHEMBL9235150 | 0.77 | PLOD2 (0.41) | KMT2ALMNAMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541182-A | Benzodiazepine aryl urea derivatives | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-07-30 | — | — | US | disclosed |
| EP-0591529-A1 | NOVEL BENZODIAZEPINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1994-04-13 | — | — | EP | disclosed |