Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11010126 | 0.81 | DNM1 (0.47) | DNM1ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL2398433 | 0.79 | DNM1 (0.41) | DNM1ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL1818543 | 0.77 | DNM1 (0.44) | DNM1ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL4510013 | 0.76 | DNM1 (0.36) | DNM1ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL6752694 | 0.76 | TSHR (0.40) | DNM1ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL15384183 | 0.76 | DNM1 (0.42) | DNM1ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL6273275 | 0.76 | DNM1 (0.42) | DNM1ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL4510009 | 0.75 | DNM1 (0.35) | DNM1ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL9480754 | 0.74 | TSHR (0.40) | DNM1ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL278531 | 0.72 | TSHR (0.37) | DNM1ALDH1A1CNR1CNR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719273-A1 | NUCLEOTIDE ANALOGS | GILEAD SCIENCES, INC. (US) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007920-A1 | NUCLEOTIDE ANALOGS | GILEAD SCIENCES, INC. (US) | 1995-03-23 | — | — | WO | disclosed |