Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11010126 | 0.82 | DNM1 (0.47) | DNM1ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL2398433 | 0.80 | DNM1 (0.41) | DNM1ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL1818543 | 0.79 | DNM1 (0.44) | DNM1ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL6752694 | 0.78 | TSHR (0.40) | DNM1ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL15384183 | 0.77 | DNM1 (0.42) | DNM1ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL6273275 | 0.77 | DNM1 (0.42) | DNM1ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL4510009 | 0.76 | DNM1 (0.35) | DNM1ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL9235342 | 0.76 | DNM1 (0.35) | DNM1ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL8129244 | 0.76 | DNM1 (0.43) | DNM1ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL9480754 | 0.75 | TSHR (0.40) | DNM1ALDH1A1CNR1CNR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281054-A1 | COMPOSITIONS AND METHODS COMPRISING CAPURAMYCIN ANALOGUES | SEQUELLA, INC. | 2009-11-12 | — | — | US | disclosed |
| EP-1361225-B1 | COMPOUNDS SUBSTITUTED WITH BICYCLIC AMINO GROUPS | SANKYO CO (JP) | 2007-11-07 | — | — | EP | disclosed |
| US-7091352-B2 | Compounds substituted with bicyclic amino groups | SANKYO COMPANY, LIMITED (JP) | 2006-08-15 | — | — | US | disclosed |
| EP-1186302-B1 | OCULAR TENSION LOWERING COMPOSITION FOR TOPICAL ADMINSTRATION | SANKYO CO (JP) | 2005-05-18 | — | — | EP | disclosed |
| US-6844173-B2 | Strain of Streptomyces griseus | SANKYO COMPANY, LIMITED (JP) | 2005-01-18 | — | — | US | disclosed |
| US-6777436-B2 | SYNERGISTIC MIXTURE OF ANGIOTENSIN INHIBITORS, BORIC ACID, ETHYLENEDIAMINETETRAACETIC ACID AND ACTIVE DRUG | SANKYO COMPANY, LIMITED (JP) | 2004-08-17 | — | — | US | disclosed |
| US-20040147525-A1 | Compounds substituted with bicyclic amino groups | SANKYO COMPANY, LIMITED (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1361225-A1 | COMPOUNDS SUBSTITUTED WITH BICYCLIC AMINO GROUPS | Sankyo Company, Limited (JP) | 2003-11-12 | — | — | EP | disclosed |
| US-20020147211-A1 | Intraocular tension lowering compositions for topical administration | SANKYO COMPANY, LIMITED (JP) | 2002-10-10 | — | — | US | disclosed |
| US-6448247-B1 | TACHYKININ RECEPTOR ANTAGONIST; ESPECIALLY TO THE RECEPTORS FOR SUBSTANCE P (WHICH RECEPTORS ARE GENERALLY REFERRED TO AS ?NEUROKININ 1 RECEPTORS?) | SANKYO COMPANY, LIMITED (JP) | 2002-09-10 | — | — | US | disclosed |
| EP-1186302-A1 | OCULAR TENSION LOWERING COMPOSITION FOR TOPICAL ADMINSTRATION | Sankyo Company, Limited (JP) | 2002-03-13 | — | — | EP | disclosed |
| EP-0776893-B1 | Azaheterocyclic compounds having tachykinin receptor antagonist activity; Nk1 and NK2 | SANKYO CO (JP) | 2002-02-27 | — | — | EP | disclosed |
| WO-2001002413-A1 | BAFIlOMYCIN DERIVATIVES WITH ANTICANCER ACTIVITY | INSTITUTO BIOMAR S.A. (ES) | 2001-01-11 | — | — | WO | disclosed |
| US-6159967-A | Heterocyclic compounds having tachykinin receptor antagonist activity their preparation and their use | SANKYO COMPANY, LIMITED (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-0776893-A1 | Azaheterocyclic compounds having tachykinin receptor antagonist activity; Nk1 and NK2 | SANKYO COMPANY LIMITED (JP) | 1997-06-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281054-A1 | COMPOSITIONS AND METHODS COMPRISING CAPURAMYCIN ANALOGUES | TTPA, PHOSPHO1, CAPG | DNM1 1762/4885ALDH1A1 2628/4885CNR1 4114/4885 |
| US-20020147211-A1 | Intraocular tension lowering compositions for topical administration | AGT, ECE1, AGTR1 | DNM1 815/4885ALDH1A1 3001/4885CNR1 2385/4885 |
| US-20040147525-A1 | Compounds substituted with bicyclic amino groups | IL2, IL1B, IL4I1 | DNM1 4716/4885ALDH1A1 507/4885CNR1 1188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.