Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 4/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232639 | 0.82 | CA1 (0.68) | SMN1; SMN2LMNACA12CA1CA2 | |
| SCHEMBL9236170 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNACA12CA1CA2 | |
| SCHEMBL9236173 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNACA12CA1CA2 | |
| SCHEMBL12391228 | 0.71 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNACA12CA1CA2 | |
| SCHEMBL24270457 | 0.70 | LMNA (0.58) | SMN1; SMN2LMNACA12CA1CA2 | |
| Bromide SCHEMBL17079938 | 0.69 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNACA12CA1CA2 | |
| SCHEMBL9309031 | 0.68 | KMT2A (0.61) | CA12CA1CA2CA9HTT | |
| SCHEMBL11777752 | 0.68 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNACA12CA1CA2 | |
| SCHEMBL28630539 | 0.66 | HTT (0.55) | CA1CA2CA9HTTCYP2C9 | |
| SCHEMBL11826091 | 0.66 | CA1 (0.55) | SMN1; SMN2LMNACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632040-A1 | Antibacterial imidazole derivatives | Takeda Chemical Industries, Ltd. (JP) | 1995-01-04 | — | — | EP | disclosed |