Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18091486 | 0.76 | ALDH1A1 (0.36) | BRD4OPRM1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL6183360 | 0.76 | BRD4 (0.48) | BRD4OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL7270574 | 0.74 | ALDH1A1 (0.41) | SMN1; SMN2TSHRALDH1A1GAALMNA | |
| SCHEMBL7276909 | 0.73 | ALDH1A1 (0.40) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL14803275 | 0.70 | ALDH1A1 (0.35) | OPRM1TSHRALDH1A1GAALMNA | |
| SCHEMBL7301462 | 0.69 | BRD4 (0.54) | BRD4OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL16836131 | 0.68 | BRD4 (0.52) | BRD4OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL21142455 | 0.68 | BRD4 (0.68) | BRD4OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL31034902 | 0.67 | BRD4 (0.51) | BRD4OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL30801469 | 0.67 | BRD4 (0.51) | BRD4OPRM1OPRD1OPRK1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635500-A1 | 5,6-Dihydro-(4H)1,3-oxazine and -thiazine derivatives as insecticides | YASHIMA CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-01-25 | — | — | EP | disclosed |