Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.48 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9237268 | 0.86 | RAB9A (0.44) | MAPK14ALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL9239763 | 0.85 | RAB9A (0.43) | MAPK14NR2E3ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9236956 | 0.84 | KMT2A (0.42) | MAPK14ALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL9235020 | 0.82 | ALDH1A1 (0.50) | MAPK14ALDH1A1MAPTKMT2ANPSR1 | |
| SCHEMBL9232300 | 0.81 | RAB9A (0.63) | MAPK14ALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL9237515 | 0.81 | PREP (0.43) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL9232257 | 0.81 | RAB9A (0.43) | ALDH1A1HTTSMN1; SMN2MAPTKMT2A | |
| SCHEMBL9238789 | 0.81 | RAB9A (0.40) | ALDH1A1HTTSMN1; SMN2NPBWR1MAPT | |
| SCHEMBL9237988 | 0.80 | KMT2A (0.68) | NR2E3ALDH1A1HTTSMN1; SMN2NPBWR1 | |
| SCHEMBL9239759 | 0.79 | RAB9A (0.44) | MAPK14ALDH1A1KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665223-A1 | Antitumor agent, novel 3(2H)-pyridazinone derivatives and their preparation | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |