Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | GPR183 | P32249 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9239763 | 0.87 | RAB9A (0.43) | RAB9AL3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL9236870 | 0.86 | MAPK14 (0.48) | RAB9ANPC1MEN1KMT2AGALR3 | |
| SCHEMBL9236956 | 0.86 | KMT2A (0.42) | RAB9AL3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL9232257 | 0.85 | RAB9A (0.43) | RAB9AL3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL9235020 | 0.84 | ALDH1A1 (0.50) | RAB9AL3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL9239759 | 0.83 | RAB9A (0.44) | RAB9AL3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL9232300 | 0.83 | RAB9A (0.63) | RAB9AL3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL9237515 | 0.82 | PREP (0.43) | RAB9AL3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL9238789 | 0.82 | RAB9A (0.40) | RAB9AL3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL15566568 | 0.76 | RAB9A (0.52) | RAB9AL3MBTL1NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665223-A1 | Antitumor agent, novel 3(2H)-pyridazinone derivatives and their preparation | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |