SCHEMBL9237174

SCHEMBL9237174

COC(=O)CCc1ccc(C(O)Cc2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.50
CA12 O43570 1/20 0.49
CA7 P43166 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49
FFAR1 O14842 2/20 0.49
ALDH1A1 P00352 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TRPA1 O75762 1/20 0.48
KEAP1 Q14145 1/20 0.47
PPARG P37231 1/20 0.47
PPARA Q07869 1/20 0.47
PTPN1 P18031 2/20 0.46
KDM4E B2RXH2 2/20 0.46
GAA P10253 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ADRB2 P07550 1/20 0.46
ADRB1 P08588 1/20 0.46
RECQL P46063 1/20 0.46
TRPV1 Q8NER1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8894974 0.92 ADRB3 (0.49) CA12CA7CA9CA14ALDH1A1
SCHEMBL9231232 0.90 ADRB3 (0.47) CA12CA7CA9CA14FFAR1
Methyl 3-Phenylpropanoate SCHEMBL168711 0.84 TDP1 (0.68) TDP1CA12CA7CA9CA14
SCHEMBL10649974 0.83 PTGER2 (0.48) TDP1CA12CA7CA9CA14
Methyl 3-Phenylpropanoate SCHEMBL213543 0.82 KEAP1 (0.70) TDP1CA12CA7CA9CA14
Methyl 3-Phenylpropanoate SCHEMBL1893702 0.82 TDP1 (0.66) TDP1CA12CA7CA9CA14
Methyl 3-Phenylpropanoate SCHEMBL27315471 0.82 TDP1 (0.66) TDP1CA12CA7CA9CA14
Methyl 3-Phenylpropanoate SCHEMBL27447160 0.82 TDP1 (0.66) TDP1CA12CA7CA9CA14
SCHEMBL9233223 0.82 FAAH (0.49) CA12CA7CA9CA14ALDH1A1
SCHEMBL9122892 0.81 FFAR1 (0.55) TDP1FFAR1ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0663392-A1 BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF HOKURIKU SEIYAKU CO., LTD. (JP) 1995-07-19 EP disclosed