Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15222217 | 0.79 | HTT (0.59) | ALDH1A1MEN1KMT2AHTTAURKA | |
| SCHEMBL15217707 | 0.77 | MAPT (0.58) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL28489651 | 0.73 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL134274 | 0.71 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL29532939 | 0.71 | KDM4E (0.74) | ALDH1A1L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL8325338 | 0.71 | KDM4E (0.74) | ALDH1A1L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL8776502 | 0.70 | HTT (0.61) | ALDH1A1L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL17690322 | 0.70 | KMT2A (0.53) | ALDH1A1L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL17716230 | 0.70 | KMT2A (0.64) | ALDH1A1L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL159829 | 0.70 | KDM4E (0.53) | ALDH1A1L3MBTL1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130225578-A1 | 7-CYCLYLQUINAZOLINE DERIVATIVES AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2013-08-29 | — | — | US | disclosed |
| EP-0665224-A1 | PYRIMIDINE DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225578-A1 | 7-CYCLYLQUINAZOLINE DERIVATIVES AND METHODS OF USE THEREOF | JAK2, JAK3, TYK2 | ALDH1A1 4574/4885L3MBTL1 3033/4885MEN1 3010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.