Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9237208 | 0.86 | TDP1 (0.47) | LMNAL3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL2484224 | 0.85 | LMNA (0.52) | LMNAL3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL9239665 | 0.85 | TDP1 (0.48) | LMNAL3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL9238606 | 0.84 | KDM4E (0.50) | LMNAKDM4ECYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9242423 | 0.84 | PSEN1 (0.45) | LMNAL3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL9239997 | 0.83 | TDP1 (0.42) | LMNAL3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL9266851 | 0.82 | MCL1 (0.46) | KDM4EALDH1A1TSHRADORA3TP53 | |
| SCHEMBL9242590 | 0.81 | RXFP1 (0.52) | RXFP1PHGDHMEN1KMT2A | |
| SCHEMBL6608082 | 0.80 | MAPT (0.51) | LMNARXFP1ALDH1A1HPGDTP53 | |
| SCHEMBL9242465 | 0.78 | TDP1 (0.45) | LMNAL3MBTL1TDP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639573-A1 | Benzocondensed five membered heterocycles, process of their preparation, their use as drug, as diagnostic means and pharmaceuticals containing it | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-02-22 | — | — | EP | disclosed |