Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 6/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9237208 | 0.90 | TDP1 (0.47) | TDP1ALDH1A1LMNAL3MBTL1CCR2 | |
| SCHEMBL9242423 | 0.88 | PSEN1 (0.45) | TDP1ALDH1A1LMNAL3MBTL1CCR2 | |
| SCHEMBL9237671 | 0.85 | LMNA (0.50) | TDP1ALDH1A1LMNAL3MBTL1ALOX15 | |
| SCHEMBL9243077 | 0.85 | CCR2 (0.47) | TDP1ALDH1A1CCR2MAPTKMT2A | |
| SCHEMBL9242465 | 0.85 | TDP1 (0.45) | TDP1ALDH1A1LMNAL3MBTL1CCR2 | |
| SCHEMBL2484224 | 0.84 | LMNA (0.52) | TDP1ALDH1A1LMNAL3MBTL1CCR2 | |
| SCHEMBL9239997 | 0.82 | TDP1 (0.42) | TDP1ALDH1A1LMNAL3MBTL1CCR2 | |
| SCHEMBL8689838 | 0.78 | ALDH1A1 (0.54) | TDP1ALDH1A1LMNAL3MBTL1CCR2 | |
| SCHEMBL9241443 | 0.75 | CCR2 (0.45) | TDP1LMNAL3MBTL1CCR2TP53 | |
| SCHEMBL20037044 | 0.73 | TDP1 (0.65) | TDP1ALDH1A1LMNAL3MBTL1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639573-A1 | Benzocondensed five membered heterocycles, process of their preparation, their use as drug, as diagnostic means and pharmaceuticals containing it | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-02-22 | — | — | EP | disclosed |