SCHEMBL9239013

SCHEMBL9239013

CC(=NOC(=O)Cl)c1ccc(Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
POLB P06746 2/20 0.50
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
MAPT P10636 4/20 0.48
CASP3 P42574 2/20 0.48
SENP8 Q96LD8 2/20 0.48
SENP7 Q9BQF6 2/20 0.48
SENP6 Q9GZR1 2/20 0.48
RBBP9 O75884 1/20 0.48
RAB9A P51151 5/20 0.47
NPC1 O15118 4/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
PKM P14618 1/20 0.44
CDK5 Q00535 1/20 0.44
CDK5R1 Q15078 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8769756 1.00 LMNA (0.53) LMNACYP1A2CYP2C9CYP2C19POLB
SCHEMBL8202608 0.87 LMNA (0.54) LMNACYP1A2CYP2C9CYP2C19POLB
SCHEMBL8768841 0.83 MAPT (0.57) LMNACYP1A2POLBMAPTCASP3
SCHEMBL28353284 0.81 LMNA (0.49) LMNACYP1A2CYP2C9CYP2C19POLB
SCHEMBL11255993 0.77 NPC1 (0.53) LMNACYP1A2CYP2C9CYP2C19POLB
SCHEMBL11255995 0.77 NPC1 (0.53) LMNACYP1A2CYP2C9CYP2C19POLB
SCHEMBL2056189 0.76 LMNA (0.52) LMNACYP1A2CYP2C9CYP2C19POLB
SCHEMBL27804584 0.76 LMNA (0.52) LMNACYP1A2CYP2C9CYP2C19POLB
SCHEMBL11406624 0.76 NPC1 (0.52) LMNACYP1A2CYP2C9CYP2C19POLB
SCHEMBL11412340 0.75 LMNA (0.54) LMNACYP1A2CYP2C9CYP2C19POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995023784-A1 CARBAMOYL CARBOXYLIC ACID AMIDES, PROCESS FOR PRODUCING THEM AND THEIR USE AS FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1995-09-08 WO disclosed