Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41570 | 0.84 | CES2 (0.50) | LMNATSHRCES2CES1 | |
| SCHEMBL1272990 | 0.80 | LMNA (0.48) | LMNATSHRALOX12ACHEKEAP1 | |
| SCHEMBL3657920 | 0.79 | LMNA (0.53) | LMNATSHRALOX12ACHECNR1 | |
| SCHEMBL3681516 | 0.79 | SLC6A2 (0.50) | LMNATSHRCES2CES1SLC6A3 | |
| SCHEMBL60997 | 0.79 | LMNA (0.53) | LMNATSHRALOX12ACHECNR1 | |
| SCHEMBL12199145 | 0.79 | LMNA (0.53) | LMNATSHRALOX12ACHECNR1 | |
| SCHEMBL17923689 | 0.79 | LMNA (0.53) | LMNATSHRALOX12ACHECNR1 | |
| SCHEMBL4068746 | 0.77 | LMNA (0.50) | LMNATSHRALOX12ACHECNR1 | |
| SCHEMBL2846227 | 0.77 | LMNA (0.50) | LMNATSHRALOX12ACHEKEAP1 | |
| Methane SCHEMBL11860709 | 0.77 | LMNA (0.50) | LMNATSHRALOX12ACHECNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686635-A1 | Pyridylthiazolidinecarboxylic acid amide derivatives, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1995-12-13 | — | — | EP | claimed |
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | claimed |
| EP-0549364-A1 | Pyridylthiazolidinecarboxylic acid amide derivatives, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1993-06-30 | — | — | EP | claimed |