Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL510358 | 0.84 | GABRP (0.44) | MAOBCXCR2NPC1 | |
| SCHEMBL9237638 | 0.83 | CXCR2 (0.44) | MAOBAPPELOVL1IDO1AGXT | |
| SCHEMBL21503592 | 0.83 | MAOB (0.59) | MAOBAPPELOVL1IDO1AGXT | |
| Hydrochloric Acid SCHEMBL30744406 | 0.81 | MAOB (0.60) | MAOBAPPELOVL1IDO1AGXT | |
| Hydrochloric Acid SCHEMBL21491730 | 0.81 | MAOB (0.60) | MAOBAPPELOVL1IDO1AGXT | |
| SCHEMBL15177149 | 0.80 | ELOVL1 (0.43) | MAOBAPPELOVL1IDO1AGXT | |
| SCHEMBL510047 | 0.79 | MAOB (0.49) | MAOBAPPELOVL1IDO1AGXT | |
| Methane SCHEMBL9237648 | 0.79 | CXCR2 (0.44) | MAOBAPPELOVL1IDO1AGXT | |
| SCHEMBL3365264 | 0.79 | MEN1 (0.60) | MAOBAPPELOVL1IDO1AGXT | |
| SCHEMBL510341 | 0.77 | MAOB (0.39) | MAOBAPPELOVL1IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665223-A1 | Antitumor agent, novel 3(2H)-pyridazinone derivatives and their preparation | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |
| US-4908379-A | Insecticides, acaricides, nematocides, fungicides | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-03-13 | — | — | US | disclosed |
| EP-0339105-A1 | Nitrogen-containing heterocyclic compounds and compositions for controlling and/or preventing pests and blights (diseases) | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-11-02 | — | — | EP | disclosed |