Biphenyl

Biphenyl

SCHEMBL9239362

O=Cc1ccc(N(Cc2ccccc2)Cc2ccccc2)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.53
ALDH1A1 P00352 6/20 0.52
ALDH3A1 P30838 1/20 0.52
ALDH1A3 P47895 1/20 0.52
TSHR P16473 1/20 0.50
CNR2 P34972 5/20 0.47
KDM4E B2RXH2 4/20 0.46
MAPT P10636 4/20 0.46
LMNA P02545 3/20 0.46
MAPK1 P28482 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
HPGD P15428 2/20 0.46
KMT2A Q03164 2/20 0.46
MITF O75030 1/20 0.46
RAD52 P43351 1/20 0.46
NR1H2 P55055 2/20 0.44
NR1H3 Q13133 2/20 0.44
CYP2A6 P11509 2/20 0.43
NR3C1 P04150 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1165356 0.95 CYP2C19 (0.58) CYP2C19ALDH1A1ALDH3A1ALDH1A3TSHR
SCHEMBL4747974 0.86 TSHR (0.70) CYP2C19ALDH1A1ALDH3A1ALDH1A3TSHR
Biphenyl SCHEMBL1200005 0.82 ALDH1A1 (0.78) ALDH1A1ALDH3A1ALDH1A3TSHRCNR2
SCHEMBL11581161 0.82 ALDH1A1 (0.47) CYP2C19ALDH1A1ALDH3A1ALDH1A3TSHR
SCHEMBL7154167 0.81 CYP2C19 (0.69) CYP2C19ALDH1A1TSHRCNR2LMNA
SCHEMBL8620760 0.80 NR3C2 (0.49) CYP2C19ALDH1A1ALDH3A1ALDH1A3TSHR
SCHEMBL4403046 0.80 CYP2C19 (0.62) CYP2C19ALDH1A1TSHRCNR2KDM4E
SCHEMBL2960872 0.79 CYP2C19 (0.78) CYP2C19ALDH1A1TSHRCNR2LMNA
SCHEMBL6924153 0.79 NR3C2 (0.51) CYP2C19ALDH1A1ALDH3A1ALDH1A3TSHR
SCHEMBL11579761 0.79 ALDH1A1 (0.49) CYP2C19ALDH1A1ALDH3A1ALDH1A3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5478684-A Coating with liquid charge generation layer film including resin binder and a stabilizer; heating; hardening FUJI ELECTRIC CO., LTD. (JP) 1995-12-26 US disclosed