SCHEMBL923978

SCHEMBL923978

CC(C)(C)c1cc(N)n[nH]1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
KMT2A Q03164 2/20 0.48
MITF O75030 1/20 0.48
TP53 P04637 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.39
DYRK1A Q13627 1/20 0.36
MKNK1 Q9BUB5 1/20 0.35
MKNK2 Q9HBH9 1/20 0.35
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
GFER P55789 2/20 0.34
HSD17B10 Q99714 2/20 0.34
NPC1 O15118 1/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
PDPK1 O15530 1/20 0.33
ATM Q13315 1/20 0.33
GAA P10253 1/20 0.33
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22109258 0.82 ALDH1A1 (0.46) ALDH1A1KMT2AMITFTP53SMN1; SMN2
SCHEMBL28389237 0.79 ALDH1A1 (0.40) ALDH1A1KMT2AMITFTP53SMN1; SMN2
SCHEMBL24816445 0.77 ALDH1A1 (0.39) ALDH1A1KMT2AMITFTP53SMN1; SMN2
SCHEMBL1770329 0.76 SMN1; SMN2 (0.46) ALDH1A1KMT2AMITFTP53SMN1; SMN2
SCHEMBL10065610 0.75 GFER (0.37) ALDH1A1KMT2ASMN1; SMN2MEN1GFER
SCHEMBL2478382 0.74 MITF (0.37) ALDH1A1KMT2AMITFTP53SMN1; SMN2
SCHEMBL1205789 0.73 HPGD (0.46) KMT2ASMN1; SMN2MEN1GFERNPC1
SCHEMBL24007686 0.73 MCL1 (0.45) ALDH1A1KMT2AMITFTP53SMN1; SMN2
SCHEMBL21719245 0.71 ATM (0.39) KMT2ASMN1; SMN2MEN1GFERNPC1
SCHEMBL20681841 0.71 MAPK14 (0.38) KMT2ASMN1; SMN2MEN1GFERNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 376 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118206696-A Photo-curing 3D printing part and application thereof in foaming material 中国科学院福建物质结构研究所 2024-06-18 CN claimed
CN-118085973-A Post-chemical mechanical polishing formulations and methods of use thereof 恩特格里斯公司 2024-05-28 CN claimed
CN-118047908-A Hydrophobic ion elastomer and preparation method thereof 福建理工大学 2024-05-17 CN claimed
CN-117624491-A Self-repairing dual-curing photosensitive resin material and preparation method thereof 福建理工大学 2024-03-01 CN claimed
CN-117624537-A Solvent-free multi-time self-repairing latent polyurethane resin material and preparation method thereof 福建理工大学 2024-03-01 CN claimed
CN-111808259-B 3D printing silicone rubber and preparation method and application thereof 四川大学 2021-10-12 CN claimed
CN-111808259-A 3D printing silicone rubber and preparation method and application thereof 四川大学 2020-10-23 CN claimed
US-10351809-B2 Post chemical mechanical polishing formulations and method of use ENTEGRIS, INC. (US) 2019-07-16 US claimed
US-20180037852-A1 POST CHEMICAL MECHANICAL POLISHING FORMULATIONS AND METHOD OF USE TRUIST BANK, AS NOTES COLLATERAL AGENT 2018-02-08 US claimed
EP-3243213-A1 POST CHEMICAL MECHANICAL POLISHING FORMULATIONS AND METHOD OF USE Entegris, Inc. (US) 2017-11-15 EP claimed
EP-3099839-A1 POST CHEMICAL MECHANICAL POLISHING FORMULATIONS AND METHOD OF USE Entegris, Inc. (US) 2016-12-07 EP claimed
US-20160340620-A1 POST CHEMICAL MECHANICAL POLISHING FORMULATIONS AND METHOD OF USE ADVANCED TECH MATERIALS (US) 2016-11-24 US claimed
WO-2015116818-A1 POST CHEMICAL MECHANICAL POLISHING FORMULATIONS AND METHOD OF USE ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2015-08-06 WO claimed
EP-1732896-B1 SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) AVENTIS PHARMA INC (US) 2012-12-12 EP claimed
US-20120202795-A1 SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) AVENTIS PHARMACEUTICALS INC. (US) 2012-08-09 US claimed
US-20070032489-A1 SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) AVENTIS PHARMACEUTICALS INC. (US) 2007-02-08 US claimed
EP-1732896-A1 SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) Aventis Pharmaceuticals Inc. (US) 2006-12-20 EP claimed
WO-2005097750-A1 SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) AVENTIS PHARMACEUTICALS INC. (US) 2005-10-20 WO claimed
EP-0129830-B1 N-ALKYLAMINOPYRAZOLE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND HERBICIDES CONTAINING THE SAME SDS Biotech K.K. (JP) 1987-11-19 EP claimed
EP-0129830-A2 N-alkylaminopyrazole derivatives, process for preparing the same, and herbicides containing the same SDS Biotech K.K. (JP) 1985-01-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120202795-A1 SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) PARP1, PARP2, PARP3 ALDH1A1 280/4885KMT2A 1291/4885MITF 4676/4885
US-20070032489-A1 SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) PARP1, PARP2, PARP3 ALDH1A1 280/4885KMT2A 1291/4885MITF 4676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.