SCHEMBL5358581

SCHEMBL5358581

CCCCCCCCCCCC(C)(C)N1CN(C(C)(C)CCCCCCCCCCC)CN(C(C)(C)CCCCCCCCCCC)C1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
GGPS1 O95749 6/20 0.35
FDPS P14324 9/20 0.34
SMPD1 P17405 2/20 0.33
CES2 O00748 1/20 0.33
LPAR1 Q92633 1/20 0.33
LPAR3 Q9UBY5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19798171 0.82 TSHR (0.35) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL18671809 0.82 L3MBTL1 (0.35) TSHRTHRBGGPS1FDPS
SCHEMBL22921027 0.82 L3MBTL1 (0.35) TSHRTHRBGGPS1FDPS
SCHEMBL5295320 0.82 L3MBTL1 (0.35) TSHRTHRBGGPS1FDPS
SCHEMBL28483075 0.82 L3MBTL1 (0.35) TSHRTHRBGGPS1FDPS
SCHEMBL24276317 0.80 L3MBTL1 (0.37) TSHRTHRBGGPS1FDPS
SCHEMBL22023942 0.80 L3MBTL1 (0.37) TSHRTHRBGGPS1FDPS
SCHEMBL20877870 0.80 L3MBTL1 (0.37) TSHRTHRBGGPS1FDPS
SCHEMBL27501976 0.80 TSHR (0.33) TSHRTHRBGGPS1FDPS
SCHEMBL24130892 0.79 GNAO1 (0.38) TSHRTHRBGGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7214842-B2 Method for oligomerizing olefins BASF AKTIENGESELLSCHAFT (DE) 2007-05-08 US disclosed
US-20050165266-A1 olefin is brought into contact with a catalyst system comprising at least one transition metal complex with a polydentate complexing ligand and an alkylaluminoxane; transition metal complex is added continuously or in portions during the oligomerization. BASF AKTIENGESELLSCHAFT (DE) 2005-07-28 US disclosed
US-6844290-B1 Oligomerization catalyst BASF AKTIENGESELLSCHAFT (DE) 2005-01-18 US disclosed
EP-1171445-B1 OLIGOMERISATION CATALYST BASF AG (DE) 2004-01-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050165266-A1 olefin is brought into contact with a catalyst system comprising at least one transition metal complex with a polydentate complexing ligand and an alkylaluminoxane; transition metal complex is added continuously or in portions during the oligomerization. ALOX12, ALOX15B, ALOX15 TSHR 3306/4885THRB 3354/4885GGPS1 1303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.