SCHEMBL9239999

SCHEMBL9239999

O=C(O)COC(=O)/C=C/c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.67
AKR1B10 O60218 3/20 0.63
AKR1B1 P15121 3/20 0.63
RAB9A P51151 1/20 0.61
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
CA12 O43570 1/20 0.57
CA4 P22748 1/20 0.57
CA6 P23280 1/20 0.57
CA5A P35218 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
CA5B Q9Y2D0 1/20 0.57
ALDH1A1 P00352 3/20 0.53
MAPT P10636 2/20 0.53
HDAC3 O15379 1/20 0.53
TNKS O95271 1/20 0.53
HDAC4 P56524 1/20 0.53
HDAC1 Q13547 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9240002 1.00 LMNA (0.67) LMNAAKR1B10AKR1B1RAB9AMEN1
SCHEMBL9763118 0.86 LMNA (0.63) LMNAAKR1B10AKR1B1RAB9AMEN1
SCHEMBL11632235 0.86 LMNA (0.63) LMNAAKR1B10AKR1B1RAB9AMEN1
SCHEMBL11632240 0.86 LMNA (0.63) LMNAAKR1B10AKR1B1RAB9AMEN1
SCHEMBL28654784 0.86 LMNA (0.63) LMNAAKR1B10AKR1B1RAB9AMEN1
SCHEMBL9855968 0.85 LMNA (0.71) LMNAAKR1B10AKR1B1RAB9AMEN1
SCHEMBL9855964 0.85 LMNA (0.71) LMNAAKR1B10AKR1B1RAB9AMEN1
SCHEMBL19279512 0.85 AKR1B10 (0.83) LMNAAKR1B10AKR1B1RAB9AMEN1
SCHEMBL16234738 0.85 AKR1B10 (0.83) LMNAAKR1B10AKR1B1RAB9AMEN1
SCHEMBL9277968 0.85 AKR1B10 (0.83) LMNAAKR1B10AKR1B1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0333373-B1 Method for synthesizing acyloxycarboxylic acids CLOROX CO (US) 1995-01-04 EP disclosed
US-5091560-A Reacting hydroxycarboxylic acid and acid chloride THE CLOROX COMPANY (US) 1992-02-25 US disclosed
EP-0333373-A2 Method for synthesizing acyloxycarboxylic acids The Clorox Company (US) 1989-09-20 EP disclosed
US-4411983-A REMOVAL OF NON-IMAGE AREA WITH WATER MISCIBILITY ORGANIC SOLVENT FUJI PHOTO FILM CO., LTD. (JP) 1983-10-25 US disclosed
US-4085277-A BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1978-04-18 US disclosed
US-4001225-A Pyridyl substituted 7-αesters of 3 heterothio 7-acetamido cephalosporanic acids FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-01-04 US disclosed
US-4000133-A BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-12-28 US disclosed