SCHEMBL9240503

SCHEMBL9240503

Cc1ccc(N(c2ccc(-c3ccccc3)cc2)c2cccc(N(c3ccc(C)cc3)c3ccc(-c4ccccc4)cc3)c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.42
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
CYP2C19 P33261 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
HPGD P15428 2/20 0.41
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
HPRT1 P00492 1/20 0.40
POLB P06746 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12677676 0.94 TDP1 (0.41) TDP1KDM4EALDH1A1MAPTL3MBTL1
SCHEMBL17465483 0.94 TDP1 (0.41) TDP1KDM4EALDH1A1MAPTL3MBTL1
SCHEMBL8739746 0.94 TDP1 (0.41) TDP1KDM4EALDH1A1MAPTL3MBTL1
SCHEMBL9581209 0.94 TDP1 (0.41) TDP1KDM4EALDH1A1MAPTL3MBTL1
SCHEMBL9581153 0.94 TDP1 (0.41) TDP1KDM4EALDH1A1MAPTL3MBTL1
SCHEMBL10065957 0.94 TDP1 (0.41) TDP1KDM4EALDH1A1MAPTL3MBTL1
SCHEMBL12798298 0.94 TDP1 (0.41) TDP1KDM4EALDH1A1MAPTL3MBTL1
SCHEMBL22760589 0.94 TDP1 (0.41) TDP1KDM4EALDH1A1MAPTL3MBTL1
SCHEMBL20709531 0.94 TDP1 (0.41) TDP1KDM4EALDH1A1MAPTL3MBTL1
SCHEMBL13020714 0.94 TDP1 (0.41) TDP1KDM4EALDH1A1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1788037-B1 Titanylphthalocyanin crystal, method for preparing the same, and electrophotographic photoreceptor KYOCERA MITA CORP (JP) 2013-01-02 EP disclosed
US-20110136050-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME SHARP KABUSHIKI KAISHA (JP) 2011-06-09 US disclosed
US-20110136050-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME SHARP KABUSHIKI KAISHA (JP) 2011-06-09 US disclosed
US-20110076602-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME SHARP KABUSHIKI KAISHA (JP) 2011-03-31 US disclosed
US-20110076602-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME SHARP KABUSHIKI KAISHA (JP) 2011-03-31 US disclosed
US-7855286-B2 Titanyl phthalocyanin crystal, method for preparing the same and electrophotographic photoconductor KYOCERA MITA CORPORATION (JP) 2010-12-21 US disclosed
US-20100081073-A1 Titanyl phthalocyanin crystal, method for preparing the same and electrophotographic photoconductor KYOCERA MITA CORPORATION 2010-04-01 US disclosed
US-20100081073-A1 Titanyl phthalocyanin crystal, method for preparing the same and electrophotographic photoconductor KYOCERA MITA CORPORATION 2010-04-01 US disclosed
EP-1788037-A1 Titanylphthalocyanin crystal, method for preparing the same, and electrophotographic photoreceptor Kyocera Mita Corporation (JP) 2007-05-23 EP disclosed
US-20070111123-A1 Titanyl phthalocyanin crystal, method for preparing the same and electrophotographic photoconductor KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2007-05-17 US disclosed
US-20070111123-A1 Titanyl phthalocyanin crystal, method for preparing the same and electrophotographic photoconductor KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2007-05-17 US disclosed
EP-1093025-B1 Titanyl phthalocyanine crystal and production method of the same and electrophotosensitive material KYOCERA MITA CORP (JP) 2007-01-31 EP disclosed
EP-0687668-A2 m-Phenylenediamine derivatives and electrophotosensitive material using the same MITA INDUSTRIAL CO., LTD. (JP) 1995-12-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070111123-A1 Titanyl phthalocyanin crystal, method for preparing the same and electrophotographic photoconductor CRYZ, CRYAA, CRYAB TDP1 3217/4885KDM4E 1235/4885ALDH1A1 2438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.