SCHEMBL9240643

SCHEMBL9240643

COCOC(c1ccc(F)cc1F)C1(C(O)CC(C)C)CC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.33
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
SLC6A2 P23975 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9236809 0.77 CES2 (0.32) HSD11B1CES2CES1SLC6A2
SCHEMBL9234894 0.76 CES2 (0.33) HSD11B1CES2CES1
SCHEMBL9237186 0.73 CES2 (0.31) HSD11B1CES2CES1SLC6A2
SCHEMBL9233994 0.71 OPRM1 (0.37) CES2CES1
SCHEMBL9234003 0.64 CES2 (0.31) HSD11B1CES2CES1
SCHEMBL9237470 0.64 CES2 (0.31) HSD11B1CES2CES1
SCHEMBL1998132 0.62 CES2 (0.52) HSD11B1CES2CES1SLC6A2
SCHEMBL15853708 0.62 CES2 (0.52) HSD11B1CES2CES1SLC6A2
SCHEMBL17947416 0.62 CES2 (0.52) HSD11B1CES2CES1SLC6A2
SCHEMBL29453648 0.62 CES2 (0.52) HSD11B1CES2CES1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0670315-A1 Triazole oxime derivatives having antimycotic acitivity MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1995-09-06 EP disclosed