Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9237186 | 0.78 | CES2 (0.31) | CES2CES1HSD11B1MC4RIDO1 | |
| SCHEMBL9240643 | 0.77 | HSD11B1 (0.33) | CES2CES1HSD11B1SLC6A2 | |
| SCHEMBL9233994 | 0.76 | OPRM1 (0.37) | CES2CES1MEN1NPC1KMT2A | |
| SCHEMBL9234894 | 0.76 | CES2 (0.33) | CES2CES1HSD11B1MEN1KMT2A | |
| SCHEMBL9238593 | 0.65 | CES2 (0.39) | CES2CES1HSD11B1MC4RIDO1 | |
| SCHEMBL8807188 | 0.64 | IDO1 (0.43) | CES2CES1MC4RIDO1TDO2 | |
| SCHEMBL3909922 | 0.62 | CES2 (0.55) | CES2CES1MC4RIDO1TDO2 | |
| SCHEMBL22909980 | 0.62 | CES2 (0.47) | CES2CES1MC4RIDO1TDO2 | |
| SCHEMBL12332374 | 0.62 | TRPA1 (0.44) | CES2CES1MC4RIDO1TDO2 | |
| SCHEMBL500831 | 0.61 | APLNR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670315-A1 | Triazole oxime derivatives having antimycotic acitivity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-06 | — | — | EP | disclosed |