Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLN | Q9BYT8 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 3/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8515469 | 0.91 | PIN1 (0.39) | NLNMETAP2PIN1METAP1 | |
| SCHEMBL6856397 | 0.86 | NAMPT (0.42) | NPC1RAB9ANAMPTCYP1A2 | |
| SCHEMBL8513563 | 0.83 | CCKBR (0.39) | METAP2PIN1 | |
| N-Histidyl-2-Aminonaphthalene (Betana) SCHEMBL29941314 | 0.82 | MAPT (0.46) | NLNNPC1RAB9AKDM4EMEN1 | |
| N-Histidyl-2-Aminonaphthalene (Betana) SCHEMBL4292342 | 0.82 | MAPT (0.46) | NLNNPC1RAB9AKDM4EMEN1 | |
| N-Histidyl-2-Aminonaphthalene (Betana) SCHEMBL4292344 | 0.82 | MAPT (0.46) | NLNNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL18064448 | 0.81 | PIN1 (0.46) | PIN1 | |
| SCHEMBL16576436 | 0.81 | PIN1 (0.46) | PIN1 | |
| SCHEMBL23573037 | 0.80 | NLN (0.64) | NLNMETAP2METAP1 | |
| SCHEMBL21795244 | 0.80 | NLN (0.64) | NLNMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633316-A1 | Lys-aminopeptidase PepN from lactobacillus delbruckii ssp. Lactis, nucleic acids coding for it, and its use in fermentation processes | EUROPEAN ECONOMIC COMMUNITY E.E.C. (LU) | 1995-01-11 | — | — | EP | disclosed |