Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 7/20 | 0.38 |
| ▸ | DHFR | P00374 | 2/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8515469 | 0.86 | PIN1 (0.39) | PIN1METAP2 | |
| SCHEMBL9242008 | 0.83 | NLN (0.41) | PIN1METAP2 | |
| SCHEMBL11224178 | 0.80 | SLC15A2 (0.43) | CCKBRPIN1 | |
| SCHEMBL731316 | 0.80 | METAP2 (0.50) | CCKBRDHFRMETAP2PPARGNR1H4 | |
| SCHEMBL16576436 | 0.79 | PIN1 (0.46) | PIN1 | |
| SCHEMBL18064448 | 0.79 | PIN1 (0.46) | PIN1 | |
| SCHEMBL31453841 | 0.79 | DPP4 (0.39) | — | |
| SCHEMBL29420173 | 0.79 | NAALAD2 (0.49) | — | |
| SCHEMBL2780879 | 0.79 | DPP4 (0.40) | FOLH1 | |
| SCHEMBL17768459 | 0.79 | DPP4 (0.40) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3269822-A1 | METHODS AND COMPOSITIONS TO DETECT A BIOLOGICAL ACTIVITY | 3M Innovative Properties Company (US) | 2018-01-17 | — | — | EP | disclosed |
| EP-2643471-B1 | METHODS AND COMPOSITIONS TO DETECT A BIOLOGICAL ACTIVITY | 3M INNOVATIVE PROPERTIES CO (US) | 2017-08-30 | — | — | EP | disclosed |
| US-9435739-B2 | Methods and compositions to detect a biological activity | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-09-06 | — | — | US | disclosed |
| EP-2643471-A1 | METHODS AND COMPOSITIONS TO DETECT A BIOLOGICAL ACTIVITY | 3M Innovative Properties Company (US) | 2013-10-02 | — | — | EP | disclosed |
| US-20130230876-A1 | METHODS AND COMPOSITIONS TO DETECT A BIOLOGICAL ACTIVITY | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-09-05 | — | — | US | disclosed |
| WO-2012071131-A1 | METHODS AND COMPOSITIONS TO DETECT A BIOLOGICAL ACTIVITY | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-05-31 | — | — | WO | disclosed |