Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4462159 | 0.80 | CYP2C19 (0.41) | GAATSHRALDH1A1HIF1ATP53 | |
| SCHEMBL2265057 | 0.79 | GAA (0.55) | GAATSHRALDH1A1HIF1ATP53 | |
| SCHEMBL31122152 | 0.78 | HSPA5 (0.57) | GAATSHRALDH1A1HIF1ATP53 | |
| SCHEMBL9721288 | 0.78 | HSPA5 (0.57) | GAATSHRALDH1A1HIF1ATP53 | |
| SCHEMBL28339376 | 0.77 | ALDH1A1 (0.44) | GAATSHRALDH1A1HIF1ATP53 | |
| SCHEMBL28845858 | 0.77 | VCAM1 (0.41) | GAAALDH1A1SMN1; SMN2HSD17B10ALOX15 | |
| SCHEMBL11232750 | 0.75 | GAA (0.47) | GAATSHRALDH1A1HIF1ATP53 | |
| SCHEMBL11583200 | 0.75 | HSPA5 (0.54) | GAATSHRALDH1A1HIF1ACYP3A4 | |
| SCHEMBL5412953 | 0.74 | GAA (0.56) | GAATSHRALDH1A1HIF1ATP53 | |
| SCHEMBL1493625 | 0.73 | THRB (0.43) | GAATSHRALDH1A1HIF1ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382633-A | Modified polymers | 3I RESEARCH EXPLOITATION LIMITED (GB) | 1995-01-17 | — | — | US | claimed |
| EP-0431015-A1 | MODIFIED POLYMERS | 3i RESEARCH EXPLOITATION LIMITED (GB) | 1991-06-12 | — | — | EP | claimed |
| EP-0357267-A1 | Modified polymers | 3i RESEARCH EXPLOITATION LIMITED (GB) | 1990-03-07 | — | — | EP | claimed |
| WO-1990001506-A1 | MODIFIED POLYMERS | 3I RESEARCH EXPLOITATION LIMITED (GB) | 1990-02-22 | — | — | WO | claimed |
| US-10266566-B2 | Protease-resistant peptide ligands | NORTH CAROLINA STATE UNIVERSITY (US) | 2019-04-23 | — | — | US | disclosed |
| US-20160159859-A1 | PROTEASE-RESISTANT PEPTIDE LIGANDS | NORTH CAROLINA STATE UNIVERSITY | 2016-06-09 | — | — | US | disclosed |
| EP-3022220-A1 | PROTEASE-RESISTANT PEPTIDE LIGANDS | North Carolina State University (US) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015009701-A1 | PROTEASE-RESISTANT PEPTIDE LIGANDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-01-22 | — | — | WO | disclosed |
| US-5382633-A | Modified polymers | 3I RESEARCH EXPLOITATION LIMITED (GB) | 1995-01-17 | — | — | US | disclosed |
| EP-0357267-A1 | Modified polymers | 3i RESEARCH EXPLOITATION LIMITED (GB) | 1990-03-07 | — | — | EP | disclosed |