SCHEMBL9242561

SCHEMBL9242561

CNc1cc(=O)[nH]c(=O)[nH]1

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.52
TP53 P04637 1/20 0.50
CA1 P00915 1/20 0.50
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
MAPT P10636 1/20 0.49
HTT P42858 1/20 0.49
KDM4C Q9H3R0 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28008499 0.98 GPR84 (0.50) GPR84TP53CA1MEN1KMT2A
SCHEMBL3236991 0.82 GPR84 (0.49) GPR84TP53CA1MEN1KMT2A
SCHEMBL14539250 0.77 SMN1; SMN2 (0.54) GPR84TP53KMT2ASMN1; SMN2MAPT
SCHEMBL18836780 0.76 GPR84 (0.52) GPR84TP53MEN1KMT2ASMN1; SMN2
SCHEMBL6999959 0.76 KDM4C (0.48) GPR84TP53MEN1KMT2ASMN1; SMN2
SCHEMBL8974784 0.76 GPR84 (0.50) GPR84TP53MEN1KMT2ASMN1; SMN2
SCHEMBL28298641 0.73 KDM4C (0.46) GPR84TP53MEN1KMT2ASMN1; SMN2
SCHEMBL8709983 0.73 GPR84 (0.77) GPR84
SCHEMBL11379657 0.73 GPR84 (0.45) GPR84TP53CA1MEN1KMT2A
SCHEMBL27172466 0.71 GPR84 (0.56) GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7188023-A None JP disclosed
CN-101003512-B Method for preparing methylamino uracil SHANGHAI CHEMICAL REAGENT RES INST 2011-03-16 CN disclosed
US-7317101-B2 Antibacterial cephalosporins SANDOZ GMBH (AT) 2008-01-08 US disclosed
US-7317101-B2 Antibacterial cephalosporins SANDOZ GMBH (AT) 2008-01-08 US disclosed
CN-101003512-A Method for preparing methylamino uracil SHANGHAI INST OF CHEMICAL AGEN (CN) 2007-07-25 CN disclosed
JP-H07188023-A VASCULARIZATION INHIBITOR TAIHO YAKUHIN KOGYO KK 1995-07-25 JP disclosed