Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848895 | 0.80 | — | — | |
| SCHEMBL5804452 | 0.79 | — | — | |
| SCHEMBL14586442 | 0.79 | MAPT (0.41) | ALDH1A1TSHRMAPTSMN1; SMN2DDAH1 | |
| SCHEMBL28179346 | 0.77 | — | — | |
| SCHEMBL22856074 | 0.77 | MAPT (0.46) | ALDH1A1TSHRMAPTSMN1; SMN2LMNA | |
| SCHEMBL4068835 | 0.77 | SMN1; SMN2 (0.58) | ALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL17884297 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPTSMN1; SMN2DDAH1 | |
| SCHEMBL5466809 | 0.76 | — | — | |
| SCHEMBL28273001 | 0.76 | — | — | |
| SCHEMBL1344230 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0654025-A4 | METHOD OF PREPARING OPTICALLY PURE PRECURSORS OF PAROXETINE. | SEPRACOR INC (US) | 1995-10-11 | — | — | EP | disclosed |
| EP-0654025-A1 | METHOD OF PREPARING OPTICALLY PURE PRECURSORS OF PAROXETINE | SEPRACOR, INC. (US) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994003428-A1 | METHOD OF PREPARING OPTICALLY PURE PRECURSORS OF PAROXETINE | SEPRACOR, INC. (US) | 1994-02-17 | — | — | WO | disclosed |
| US-5258517-A | Method of preparing optically pure precursors of paroxetine | SEPRACOR, INC. (US) | 1993-11-02 | — | — | US | disclosed |