Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HRH2 | P25021 | 4/20 | 0.50 |
| ▸ | HRH1 | P35367 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337882 | 1.00 | ALDH1A1 (0.62) | ALDH1A1HTTSMN1; SMN2POLBKMT2A | |
| Hydrochloric Acid SCHEMBL10760926 | 0.98 | ALDH1A1 (0.61) | ALDH1A1HTTSMN1; SMN2POLBKMT2A | |
| SCHEMBL3270714 | 0.89 | ALDH1A1 (0.59) | ALDH1A1HTTSMN1; SMN2POLBKMT2A | |
| SCHEMBL46979 | 0.85 | SMN1; SMN2 (0.56) | ALDH1A1HTTSMN1; SMN2POLBMAPT | |
| SCHEMBL9051052 | 0.85 | ALDH1A1 (0.56) | ALDH1A1HTTSMN1; SMN2POLBKMT2A | |
| SCHEMBL6316085 | 0.83 | CYP2D6 (0.42) | ALDH1A1HTTSMN1; SMN2POLBKMT2A | |
| SCHEMBL13845058 | 0.83 | ALDH1A1 (0.55) | ALDH1A1HTTSMN1; SMN2POLBKMT2A | |
| Hydrochloric Acid SCHEMBL27445572 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HTTSMN1; SMN2POLBKMT2A | |
| SCHEMBL18482713 | 0.83 | HRH2 (0.47) | ALDH1A1HTTSMN1; SMN2POLBKMT2A | |
| SCHEMBL10985089 | 0.82 | ALDH1A1 (0.72) | ALDH1A1HTTSMN1; SMN2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220267305-A1 | MODULATORS OF ESTROGEN RECEPTOR PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. | 2022-08-25 | — | — | US | disclosed |
| CN-1033453-C | Pyridylthiazolidine carboxylic acid amide derivative and its preparing method | SANKYO CO (JP) | 1996-12-04 | — | — | CN | disclosed |
| CN-1130630-A | Pyridylthiazolidinecarboxylic acid amide derivatives, their preparation and their therapeutic uses | SANKYO CO (JP) | 1996-09-11 | — | — | CN | disclosed |
| EP-0686635-A1 | Pyridylthiazolidinecarboxylic acid amide derivatives, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1995-12-13 | — | — | EP | disclosed |
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0549364-A1 | Pyridylthiazolidinecarboxylic acid amide derivatives, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1993-06-30 | — | — | EP | disclosed |
| US-4243805-A | 3 Fluoro-10-piperazino-8-substituted 10,11-dihydrodibenzo-(bf) thiepins and method for the preparation thereof | SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU (CS) | 1981-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267305-A1 | MODULATORS OF ESTROGEN RECEPTOR PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ADRM1, MDM2, ESR2 | ALDH1A1 2935/4885HTT 607/4885SMN1; SMN2 1543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.