SCHEMBL9243238

SCHEMBL9243238

NCCCCC(C(=O)O)N(C(=O)CN)C(=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
F2 P00734 4/20 0.46
ADRA2C P18825 1/20 0.44
MMP2 P08253 2/20 0.38
MMP9 P14780 1/20 0.38
EPOR P19235 2/20 0.37
GSR P00390 1/20 0.37
CPB2 Q96IY4 2/20 0.36
RNPEP Q9H4A4 1/20 0.36
F10 P00742 1/20 0.35
DPP7 Q9UHL4 2/20 0.35
DPP8 Q6V1X1 1/20 0.35
DPP9 Q86TI2 1/20 0.35
GAA P10253 1/20 0.34
ITGB3 P05106 1/20 0.34
ITGA2B P08514 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1387797 0.95 F2 (0.43) F2ADRA2CMMP2MMP9EPOR
SCHEMBL7321837 0.91 F2 (0.50) F2ADRA2CMMP2MMP9EPOR
SCHEMBL1387992 0.91 F2 (0.50) F2ADRA2CMMP2MMP9EPOR
SCHEMBL9716623 0.91 F2 (0.50) F2ADRA2CMMP2MMP9EPOR
SCHEMBL9716684 0.87 ADRA2C (0.50) F2ADRA2CMMP2MMP9EPOR
SCHEMBL9716679 0.87 ADRA2C (0.50) F2ADRA2CMMP2MMP9EPOR
SCHEMBL15484293 0.87 ADRA2C (0.50) F2ADRA2CMMP2MMP9EPOR
SCHEMBL1387731 0.86 F2 (0.49) F2ADRA2CMMP2MMP9EPOR
SCHEMBL28238104 0.82 F2 (0.46) F2MMP2MMP9EPORCPB2
SCHEMBL4299915 0.82 GSR (0.48) GSRCPB2RNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0415470-B1 Aminopeptidase DMV CAMPINA BV (NL) 1995-01-04 EP disclosed
EP-0415470-A2 Aminopeptidase CAMPINA MELKUNIE B.V. (NL) 1991-03-06 EP disclosed