⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660407 | 0.73 | — | — | |
| SCHEMBL6063756 | 0.73 | — | — | |
| SCHEMBL6063759 | 0.73 | — | — | |
| SCHEMBL124489 | 0.69 | CA2 (0.30) | — | |
| SCHEMBL2866219 | 0.67 | — | — | |
| SCHEMBL2866222 | 0.67 | — | — | |
| SCHEMBL3183011 | 0.65 | THRB (0.35) | — | |
| SCHEMBL14938344 | 0.65 | ALDH1A1 (0.32) | — | |
| SCHEMBL14891271 | 0.62 | — | — | |
| SCHEMBL14891272 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451266-B1 | Method of manufacturing a plastic graded-index optical transmission element | MITSUBISHI RAYON CO (JP) | 1995-12-13 | — | — | EP | disclosed |
| US-5390274-A | Distributed graded index type optical transmission plastic article and method of manufacturing same | MITSUBISHI RAYON COMPANY LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0451266-A1 | Method of manufacturing a plastic graded-index optical transmission element | MITSUBISHI RAYON CO., LTD. (JP) | 1991-10-16 | — | — | EP | disclosed |