Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28516066 | 0.83 | ALDH1A1 (0.48) | TSHRALDH1A1THRB | |
| SCHEMBL12863723 | 0.81 | THRB (0.52) | TSHRALDH1A1THRBLMNACA2 | |
| SCHEMBL1243374 | 0.79 | ALDH1A1 (0.41) | TSHRALDH1A1THRB | |
| SCHEMBL809330 | 0.79 | THRB (0.53) | TSHRALDH1A1THRBLMNACA2 | |
| SCHEMBL9469752 | 0.77 | TSHR (0.48) | TSHRALDH1A1THRB | |
| SCHEMBL10537209 | 0.77 | ALDH1A1 (0.42) | TSHRALDH1A1THRB | |
| SCHEMBL5494393 | 0.77 | ALDH1A1 (0.42) | TSHRALDH1A1THRB | |
| SCHEMBL2946008 | 0.77 | TSHR (0.53) | TSHRALDH1A1THRB | |
| Bicarbonate SCHEMBL29257315 | 0.76 | THRB (0.50) | TSHRALDH1A1THRBLMNACA2 | |
| SCHEMBL728532 | 0.75 | THRB (0.59) | TSHRALDH1A1THRBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328321-B1 | Water soluble acrylic polymerisable materials, polymers made from them, and processes of making them | ALLIED COLLOIDS LTD (GB) | 1995-05-17 | — | — | EP | disclosed |
| EP-0328321-A2 | Water soluble acrylic polymerisable materials, polymers made from them, and processes of making them | Ciba Specialty Chemicals Water Treatments Limited (GB) | 1989-08-16 | — | — | EP | disclosed |
| US-4684691-A | DISPERSION | BAYER AKTIENGESELLSCHAFT (DE) | 1987-08-04 | — | — | US | disclosed |
| US-4133793-A | Compositions containing novel methacrylic polymers having allyl functionality | ROHM AND HAAS COMPANY (US) | 1979-01-09 | — | — | US | disclosed |