Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778662 | 1.00 | MAPK8 (0.39) | MAPK8MAPTSMN1; SMN2NPC1TP53 | |
| SCHEMBL9243766 | 1.00 | MAPK8 (0.39) | MAPK8MAPTSMN1; SMN2NPC1TP53 | |
| SCHEMBL8568879 | 0.81 | NUDT1 (0.39) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL882972 | 0.79 | MAPK8 (0.47) | MAPK8MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL8564074 | 0.73 | MAPK8 (0.36) | MAPK8MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL24351052 | 0.69 | NUDT1 (0.39) | MAPK8MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2221308 | 0.69 | KDM4E (0.40) | MAPK8MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3817284 | 0.69 | MAPK8 (0.41) | MAPK8MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8309216 | 0.68 | MAPT (0.60) | MAPTKDM4EACACBUSP2HPGD | |
| SCHEMBL526845 | 0.67 | NUDT1 (0.38) | MAPK8MAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439910-A | For applying to plants, seeds or soils | ZENECA LIMITED (GB) | 1995-08-08 | — | — | US | disclosed |
| EP-0586393-A1 | SUBSTITUTED-2-PHENYL-3-METHOXYPROPENOATES AS FUNGICIDES | ZENECA LIMITED (GB) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992018487-A1 | SUBSTITUTED-2-PHENYL-3-METHOXYPROPENOATES AS FUNGICIDES | ZENECA LIMITED (GB) | 1992-10-29 | — | — | WO | disclosed |