Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19615617 | 0.98 | KDM4E (0.44) | KDM4ENOS3NOS2POLBKMT2A | |
| Hydrochloric Acid SCHEMBL19615616 | 0.98 | KDM4E (0.44) | KDM4ENOS3NOS2POLBKMT2A | |
| SCHEMBL8344177 | 0.85 | KDM4E (0.49) | KDM4ENOS3NOS2POLBKMT2A | |
| SCHEMBL9243795 | 0.85 | KDM4E (0.49) | KDM4ENOS3NOS2POLBKMT2A | |
| SCHEMBL8570227 | 0.85 | KDM4E (0.49) | KDM4ENOS3NOS2POLBKMT2A | |
| SCHEMBL13593104 | 0.73 | KDM4E (0.53) | KDM4EPOLBKMT2A | |
| SCHEMBL19631984 | 0.72 | IDO1 (0.31) | — | |
| SCHEMBL19632007 | 0.71 | KDM4E (0.44) | KDM4E | |
| SCHEMBL6840488 | 0.71 | KDM4E (0.55) | KDM4ENOS3NOS2KMT2A | |
| SCHEMBL8284487 | 0.71 | KDM4E (0.55) | KDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198785-A1 | OXIME DERIVATIVES USEFUL AS INHIBITORS OF HISTONE DEMETHYLASE KDM4C | IEO - ISTITUTO EUROPEO DI ONCOLOGIA S.R.L. (IT) | 2017-11-23 | — | — | WO | disclosed |