SCHEMBL92438

SCHEMBL92438

CCCN(CCC)c1ccc(N=C2C=C(NC(=O)c3cccnc3)C(=O)C(Cl)=C2CC)cc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.46
NPSR1 Q6W5P4 3/20 0.46
GFER P55789 2/20 0.46
ALDH1A1 P00352 7/20 0.42
LMNA P02545 1/20 0.42
SMN1; SMN2 Q16637 4/20 0.41
RAB9A P51151 4/20 0.41
NPC1 O15118 3/20 0.41
CYP2C19 P33261 1/20 0.40
NAMPT P43490 1/20 0.39
GAA P10253 2/20 0.38
POLB P06746 2/20 0.38
TSHR P16473 1/20 0.38
KDM4E B2RXH2 1/20 0.37
TP53 P04637 2/20 0.37
ROCK2 O75116 1/20 0.36
ROCK1 Q13464 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL92478 0.93 NPSR1 (0.55) MAPTNPSR1GFERALDH1A1LMNA
SCHEMBL12723138 0.91 MAPT (0.47) MAPTNPSR1GFERALDH1A1LMNA
SCHEMBL10000299 0.83 ESRRG (0.32)
SCHEMBL10000295 0.77 EGFR (0.34) MAPTALDH1A1SMN1; SMN2RAB9ANPC1
SCHEMBL12652320 0.74 MEN1 (0.36) MAPTALDH1A1
SCHEMBL12723133 0.74 RAB9A (0.53) MAPTNPSR1ALDH1A1LMNASMN1; SMN2
SCHEMBL56041 0.72 RORC (0.32)
SCHEMBL14157756 0.72 ESRRG (0.43) MAPTNPSR1GFERALDH1A1LMNA
SCHEMBL13911583 0.71 TDP1 (0.42) MAPTNPSR1GFERALDH1A1LMNA
SCHEMBL14573679 0.70 MAPT (0.34) MAPTNPSR1GFERALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129309-B2 Multilayer; substrate with at least three heat sensitive transfer sheets containing dyes and resins, heat resistant slipping layers; containing polyvinyl butyral and polyvinyl acetate FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8129309-B2 Multilayer; substrate with at least three heat sensitive transfer sheets containing dyes and resins, heat resistant slipping layers; containing polyvinyl butyral and polyvinyl acetate FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8119562-B2 Heat-sensitive transfer sheet and image-forming method using heat-sensitive transfer system FUJIFILM CORPORATION (JP) 2012-02-21 US disclosed
US-8119562-B2 Heat-sensitive transfer sheet and image-forming method using heat-sensitive transfer system FUJIFILM CORPORATION (JP) 2012-02-21 US disclosed
US-8067336-B2 Polyethylene innermost surface layer FUJIFILM CORPORATION (JP) 2011-11-29 US disclosed
US-8067336-B2 Polyethylene innermost surface layer FUJIFILM CORPORATION (JP) 2011-11-29 US disclosed
US-8017552-B2 Has thermal transfer layer on a support, can stably keep up good capability of peeling off an image-receiving sheet without being affected by properties of a support, running stability FUJIFILM CORPORATION (JP) 2011-09-13 US disclosed
US-8017552-B2 Has thermal transfer layer on a support, can stably keep up good capability of peeling off an image-receiving sheet without being affected by properties of a support, running stability FUJIFILM CORPORATION (JP) 2011-09-13 US disclosed
US-8012909-B2 Receiver sheet includes receptor layer containing yellow, cyan, magenta dyes; superimposing heat sensitive transfer sheet ; heating; process control FUJIFILM CORPORATION (JP) 2011-09-06 US disclosed
US-8012909-B2 Receiver sheet includes receptor layer containing yellow, cyan, magenta dyes; superimposing heat sensitive transfer sheet ; heating; process control FUJIFILM CORPORATION (JP) 2011-09-06 US disclosed
US-20080254383-A1 IMAGE-FORMING METHOD USING HEAT-SENSITIVE TRANSFER SYSTEM FUJIFILM CORPORATION (JP) 2008-10-16 US disclosed
US-20080254383-A1 IMAGE-FORMING METHOD USING HEAT-SENSITIVE TRANSFER SYSTEM FUJIFILM CORPORATION (JP) 2008-10-16 US disclosed
US-20080254981-A1 HEAT-SENSITIVE TRANSFER IMAGE-FORMING METHOD FUJIFILM CORPORATION (JP) 2008-10-16 US disclosed
US-20080254981-A1 HEAT-SENSITIVE TRANSFER IMAGE-FORMING METHOD FUJIFILM CORPORATION (JP) 2008-10-16 US disclosed
US-20080248949-A1 HEAT-SENSITIVE TRANSFER SHEET AND IMAGE-FORMATION METHOD FUJIFILM CORPORATION (JP) 2008-10-09 US disclosed
US-20080248949-A1 HEAT-SENSITIVE TRANSFER SHEET AND IMAGE-FORMATION METHOD FUJIFILM CORPORATION (JP) 2008-10-09 US disclosed
US-20080081766-A1 IMAGE-FORMING METHOD USING HEAT-SENSITIVE TRANSFER SYSTEM FUJIFILM CORPORATION (JP) 2008-04-03 US disclosed
US-20080081766-A1 IMAGE-FORMING METHOD USING HEAT-SENSITIVE TRANSFER SYSTEM FUJIFILM CORPORATION (JP) 2008-04-03 US disclosed
US-20070213217-A1 Image-forming method using thermal transfer system FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed
US-20070213217-A1 Image-forming method using thermal transfer system FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed