SCHEMBL56041

SCHEMBL56041

CCCN(CCC)c1ccc(N=C2C=C(NC(C)=O)C(=O)C(Cl)=C2C)cc1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RORC P51449 3/20 0.32
EGFR P00533 1/20 0.32
ERBB2 P04626 1/20 0.32
GHSR Q92847 1/20 0.32
ESRRG P62508 1/20 0.31
CNR2 P34972 1/20 0.31
PABPC1 P11940 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12106906 0.96 GHSR (0.36) GHSRESRRGCNR2
SCHEMBL12106921 0.91 ALDH1A1 (0.38) ESRRGCNR2
SCHEMBL12106907 0.90 MAPT (0.32) EGFRERBB2GHSRCNR2
SCHEMBL10000299 0.88 ESRRG (0.32) RORCEGFRERBB2ESRRGCNR2
SCHEMBL12106911 0.87 GHSR (0.36) GHSRESRRG
SCHEMBL10000295 0.82 EGFR (0.34) EGFRERBB2CNR2
SCHEMBL12723138 0.82 MAPT (0.47)
SCHEMBL12106903 0.82 HDAC3 (0.37) CNR2
SCHEMBL12106917 0.82 MAPT (0.36) ESRRG
SCHEMBL12652320 0.81 MEN1 (0.36) EGFRERBB2ESRRGCNR2PABPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129311-B2 Heat-sensitive transfer image-receiving sheet FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8129311-B2 Heat-sensitive transfer image-receiving sheet FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8093181-B2 Thermal transfer member, thermal transfer member set, and recording method SONY CORPORATION (JP) 2012-01-10 US disclosed
US-8052785-B2 Polymer containing image receiver sheet on support FUJIFILM CORPORATION (JP) 2011-11-08 US disclosed
US-20090197024-A1 HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET FUJIFILM CORPORATION (JP) 2009-08-06 US disclosed
US-20090197024-A1 HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET FUJIFILM CORPORATION (JP) 2009-08-06 US disclosed
US-20090186172-A1 THERMAL TRANSFER MEMBER, THERMAL TRANSFER MEMBER SET, AND RECORDING METHOD SONY CORPORATION (JP) 2009-07-23 US disclosed
US-20080242542-A1 INDANILINE DYE, THERMAL TRANSFER RECORDING INK SHEET, THERMAL TRANSFER RECORDING METHOD, COLOR TONER, INKJET INK, AND COLOR FILTER FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080242542-A1 INDANILINE DYE, THERMAL TRANSFER RECORDING INK SHEET, THERMAL TRANSFER RECORDING METHOD, COLOR TONER, INKJET INK, AND COLOR FILTER INMT, TYR, IK RORC 816/4885EGFR 2586/4885ERBB2 1100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.