Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 2/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CLPP | Q16740 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251207 | 0.92 | P2RX3 (0.37) | GNRHRP2RX3KCNH2KMT2APLK1 | |
| SCHEMBL9245510 | 0.91 | P2RX3 (0.40) | P2RX3TDO2 | |
| SCHEMBL9156137 | 0.91 | KMT2A (0.37) | GNRHRKMT2A | |
| SCHEMBL9249926 | 0.83 | PLK1 (0.41) | GNRHRKMT2APLK1IDO1TDO2 | |
| SCHEMBL9254275 | 0.83 | P2RX3 (0.40) | P2RX3 | |
| SCHEMBL9160543 | 0.83 | MIF (0.37) | GNRHRKMT2ACNR1 | |
| SCHEMBL9243531 | 0.80 | ADORA3 (0.37) | KMT2APLK1 | |
| SCHEMBL9158679 | 0.78 | TDP1 (0.37) | PLK1 | |
| SCHEMBL9249959 | 0.76 | KDM4E (0.52) | GNRHRP2RX3KCNH2KMT2ACNR1 | |
| SCHEMBL9157717 | 0.75 | ALDH1A1 (0.37) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376223-A2 | Azaazulene derivative, process for preparing the same, and antiallergic agent and antiinflammatory agent containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1990-07-04 | — | — | EP | claimed |
| US-RE34918-E | Antihistamines, muscle relaxants | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| US-5013736-A | 5-lipoxygenase inhibitors, smooth muscle relaxants | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-05-07 | — | — | US | disclosed |
| EP-0376223-A2 | Azaazulene derivative, process for preparing the same, and antiallergic agent and antiinflammatory agent containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1990-07-04 | — | — | EP | disclosed |