SCHEMBL9244115

SCHEMBL9244115

CC1(C)CC(OC(=O)CCCCCCCCC(=O)OC2CC(C)(C)N(OC(N)=O)C(C)(C)C2)CC(C)(C)N1OC(N)=O

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
GAA P10253 1/20 0.45
NAAA Q02083 2/20 0.42
ALDH1A1 P00352 1/20 0.41
ESR1 P03372 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TSHR P16473 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.38
EPHX2 P34913 6/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1948723 0.87 TSHR (0.53) KMT2AMEN1GAANAAAALDH1A1
SCHEMBL9440185 0.85 TSHR (0.55) KMT2AMEN1GAANAAAALDH1A1
SCHEMBL1138686 0.84 NAAA (0.55) KMT2AMEN1GAANAAATSHR
SCHEMBL9745230 0.84 KMT2A (0.48) KMT2AMEN1GAANAAAALDH1A1
SCHEMBL7471002 0.83 NAAA (0.45) KMT2AMEN1GAANAAAALDH1A1
SCHEMBL18544072 0.83 NAAA (0.45) KMT2AMEN1GAANAAAALDH1A1
SCHEMBL9400337 0.83 NAAA (0.54) KMT2AMEN1GAANAAATSHR
SCHEMBL12862768 0.83 KMT2A (0.43) KMT2AMEN1GAANAAAALDH1A1
SCHEMBL1138932 0.82 NAAA (0.52) KMT2AMEN1GAANAAAALDH1A1
SCHEMBL10430889 0.82 NAAA (0.52) KMT2AMEN1GAANAAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0467849-B1 Stabilized monomer compositions CIBA GEIGY AG (CH) 1995-04-05 EP claimed
US-5300647-A Light stabilizers for polyolefins, other polymers CIBA-GEIGY CORPORATION (US) 1994-04-05 US claimed
EP-0467849-A1 Stabilized monomer compositions CIBA-GEIGY AG (CH) 1992-01-22 EP claimed
EP-0467849-B1 Stabilized monomer compositions CIBA GEIGY AG (CH) 1995-04-05 EP disclosed
US-5300647-A Light stabilizers for polyolefins, other polymers CIBA-GEIGY CORPORATION (US) 1994-04-05 US disclosed
EP-0309400-B1 N-acyloxy hindered amine stabilizers CIBA GEIGY AG (CH) 1994-03-02 EP disclosed
EP-0467849-A1 Stabilized monomer compositions CIBA-GEIGY AG (CH) 1992-01-22 EP disclosed
EP-0467844-A2 Prevention of oxidation in petrochemical extraction solvents CIBA-GEIGY AG (CH) 1992-01-22 EP disclosed
EP-0309400-A2 N-acyloxy hindered amine stabilizers CIBA-GEIGY AG (CH) 1989-03-29 EP disclosed