Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11399937 | 0.81 | CA12 (0.51) | TPMTGAATAS1R3TAS1R1POLB | |
| SCHEMBL31159539 | 0.76 | HDAC1 (0.50) | GAASMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL13572997 | 0.72 | TPMT (0.50) | TPMTGAATAS1R3TAS1R1POLB | |
| SCHEMBL6151752 | 0.70 | KDM4E (0.56) | TPMTGAATAS1R3TAS1R1POLB | |
| SCHEMBL3262883 | 0.69 | — | — | |
| SCHEMBL8432669 | 0.69 | POLB (0.62) | TPMTGAAPOLBKDM4EMEN1 | |
| SCHEMBL24931244 | 0.68 | ALDH1A1 (0.63) | GAAPOLBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL1526586 | 0.68 | CYP2C19 (0.45) | TPMTGAATAS1R3TAS1R1POLB | |
| SCHEMBL11479170 | 0.68 | GAA (0.42) | TPMTGAATAS1R3TAS1R1POLB | |
| SCHEMBL8414924 | 0.68 | NPC1 (0.48) | TPMTGAATAS1R3TAS1R1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424333-A | Anthelmintic N'-substituted-N,N'-disubstitutedhydrazines | ROHM AND HAAS COMPANY (US) | 1995-06-13 | — | — | US | disclosed |