Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 3/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31672996 | 0.88 | MAPT (0.55) | MAPTRXFP1F13A1LTB4RHDAC3 | |
| SCHEMBL10697891 | 0.86 | SMN1; SMN2 (0.52) | MAPTRXFP1F13A1HDAC3MAPK1 | |
| SCHEMBL19857034 | 0.82 | HDAC3 (0.55) | MAPTRXFP1F13A1HDAC3MAPK1 | |
| SCHEMBL8646450 | 0.80 | CA2 (0.62) | MAPTRXFP1IGF1RALOX15LTB4R | |
| SCHEMBL11153488 | 0.77 | CA2 (0.61) | MAPTCA2 | |
| SCHEMBL10971449 | 0.76 | IGF1R (0.46) | IGF1RALOX15MAPK1 | |
| SCHEMBL8242449 | 0.76 | MAPT (0.55) | MAPTRXFP1F13A1LTB4RHDAC3 | |
| SCHEMBL7278917 | 0.75 | TTR (0.46) | MAPTRXFP1ALOX15MAPK1CA2 | |
| SCHEMBL7820835 | 0.75 | MAPT (0.58) | MAPTRXFP1IGF1RALOX15F13A1 | |
| SCHEMBL28327951 | 0.75 | MAPT (0.58) | MAPTRXFP1IGF1RALOX15F13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1040062-C | Pharmacologically active compounds, methods for the preparing thereof and compositions containing same | ORION YHTYMAE OY (FI) | 1998-10-07 | — | — | CN | disclosed |
| US-5446194-A | Pharmacologically active catechol derivatives | ORION-YHTYMA OY (FI) | 1995-08-29 | — | — | US | disclosed |
| US-5283352-A | Transferase inhibitor | ORION-YHTYMA OY (FI) | 1994-02-01 | — | — | US | disclosed |
| US-5112861-A | Inhibitors of catechol-methyl-transferase enzyme, levodopa | ORION-YHTYMA OY (FI) | 1992-05-12 | — | — | US | disclosed |
| US-4963590-A | ENZYME INHIBITOR FOR TREATING PARKINSON'S DISEASE ALONG WITH DOPA;POTENTIATION | ORION-YHTYMA OY (FI) | 1990-10-16 | — | — | US | disclosed |
| CN-87108011-A | New compounds with pharmacological activity, preparation method and related components thereof | ORION YHTYMAE OY (FI) | 1988-06-08 | — | — | CN | disclosed |