SCHEMBL19857034

SCHEMBL19857034

O=C(O)CCCc1cc(O)c(O)c(O)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.55
MAPK1 P28482 1/20 0.55
ADRA1A P35348 1/20 0.55
HDAC4 P56524 1/20 0.55
SLC6A3 Q01959 1/20 0.55
HDAC1 Q13547 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
HDAC7 Q8WUI4 1/20 0.55
HDAC2 Q92769 1/20 0.55
HDAC10 Q969S8 1/20 0.55
HDAC11 Q96DB2 1/20 0.55
HDAC8 Q9BY41 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
HDAC9 Q9UKV0 1/20 0.55
HDAC5 Q9UQL6 1/20 0.55
CYP1A2 P05177 2/20 0.49
HSD17B10 Q99714 1/20 0.47
MAPT P10636 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
SELP P16109 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31672996 0.94 MAPT (0.55) HDAC3MAPK1ADRA1AHDAC4SLC6A3
SCHEMBL490873 0.87 KEAP1 (0.52) MAPK1SMN1; SMN2HSD17B10MAPTSELP
SCHEMBL9244332 0.82 MAPT (0.47) HDAC3MAPK1ADRA1AHDAC4SLC6A3
SCHEMBL6353317 0.81 HDAC3 (0.57) HDAC3MAPK1ADRA1AHDAC4SLC6A3
SCHEMBL10697891 0.80 SMN1; SMN2 (0.52) HDAC3MAPK1ADRA1AHDAC4SLC6A3
SCHEMBL18788836 0.80 IGF1R (0.67) HDAC3MAPK1ADRA1AHDAC4SLC6A3
SCHEMBL9861837 0.80 HDAC3 (0.52) HDAC3MAPK1ADRA1AHDAC4SLC6A3
SCHEMBL24264807 0.78 SMN1; SMN2 (0.53) HDAC3MAPK1ADRA1AHDAC4SLC6A3
SCHEMBL3197224 0.77 SELP (0.43) ADRA1ASLC6A3SELPSELESELL
SCHEMBL8242449 0.77 MAPT (0.55) HDAC3MAPK1ADRA1AHDAC4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3496773-B1 WETTING AGENT FORMULATION Teleflex Life Sciences Llc (US) 2025-12-17 EP disclosed
EP-3496772-B1 METHOD FOR STERILIZING A MEDICAL DEVICE Teleflex Life Sciences Llc (US) 2025-11-26 EP disclosed
US-20230105383-A1 WETTING AGENT FORMULATION Teleflex Life Sciences Llc 2023-04-06 US disclosed
US-11524096-B2 Wetting agent formulation TELEFLEX LIFE SCIENCES PTE. LTD. (SG) 2022-12-13 US disclosed
US-20190216985-A1 METHOD FOR STERILIZING A MEDICAL DEVICE Teleflex Life Sciences Llc 2019-07-18 US disclosed
EP-3496772-A1 METHOD FOR STERILIZING A MEDICAL DEVICE Teleflex Lifesciences (BM) 2019-06-19 EP disclosed
EP-3496773-A1 WETTING AGENT FORMULATION Teleflex Lifesciences (BM) 2019-06-19 EP disclosed
US-20190167849-A1 WETTING AGENT FORMULATION Teleflex Life Sciences Llc 2019-06-06 US disclosed
WO-2018028831-A1 WETTING AGENT FORMULATION TELEFLEX LIFESCIENCES (BM) 2018-02-15 WO disclosed
WO-2018029279-A1 METHOD FOR STERILIZING A MEDICAL DEVICE TELEFLEX LIFESCIENCES (BM) 2018-02-15 WO disclosed
EP-3281649-A1 WETTING AGENT FORMULATION Teleflex Lifesciences (BM) 2018-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11524096-B2 Wetting agent formulation CTSA, GLA, MGAM HDAC3 852/4885MAPK1 160/4885ADRA1A 1904/4885
US-20230105383-A1 WETTING AGENT FORMULATION CTSA, GLA, CHIA HDAC3 861/4885MAPK1 158/4885ADRA1A 1902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.