Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9244332 | 0.86 | MAPT (0.47) | SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL2415959 | 0.81 | HSD17B10 (0.50) | SMN1; SMN2MAPK1ADRA1ACYP1A2TTR | |
| SCHEMBL19857034 | 0.80 | HDAC3 (0.55) | SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL1694247 | 0.79 | TRPV1 (0.57) | SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL6353317 | 0.78 | HDAC3 (0.57) | SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL9861837 | 0.77 | HDAC3 (0.52) | SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL1206210 | 0.77 | ACLY (0.48) | ACLYFFAR1 | |
| SCHEMBL7885118 | 0.76 | HSD17B10 (0.55) | SMN1; SMN2MAPK1ADRA1ASLC6A3CYP1A2 | |
| SCHEMBL5801817 | 0.75 | CA2 (0.62) | TTRHSD17B10MAPTALDH1A1LMNA | |
| SCHEMBL29126680 | 0.75 | CYP1A2 (0.53) | SMN1; SMN2HDAC3MAPK1ADRA1AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260829-A2 | Antibodies reactive with chlorinated phenols and methods of preparing and using same | WESTINGHOUSE ELECTRIC CORPORATION (US) | 1988-03-23 | — | — | EP | disclosed |