Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.35 |
| ▸ | CALCA | P06881 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9244356 | 1.00 | PDE10A (0.35) | PDE10AALOX5APCALCACYSLTR2CYSLTR1 | |
| SCHEMBL9241773 | 0.91 | PDE10A (0.36) | PDE10ACALCAFNTAFNTBPGGT1B | |
| SCHEMBL9249928 | 0.84 | REN (0.37) | PDE10AALOX5APCYSLTR2CYSLTR1BRD4 | |
| SCHEMBL9249921 | 0.84 | REN (0.37) | PDE10AALOX5APCYSLTR2CYSLTR1BRD4 | |
| SCHEMBL9244520 | 0.82 | POLB (0.47) | FNTAFNTBPGGT1BCYP19A1 | |
| SCHEMBL9244542 | 0.82 | POLB (0.47) | FNTAFNTBPGGT1BCYP19A1 | |
| SCHEMBL9244600 | 0.81 | CALCA (0.36) | PDE10AALOX5APCALCACYSLTR2CYSLTR1 | |
| SCHEMBL9244604 | 0.81 | CALCA (0.36) | PDE10AALOX5APCALCACYSLTR2CYSLTR1 | |
| SCHEMBL8715873 | 0.81 | CYSLTR1 (0.40) | ALOX5APCYSLTR2CYSLTR1BRD4ALOX5 | |
| SCHEMBL9243625 | 0.81 | CYSLTR1 (0.40) | ALOX5APCYSLTR2CYSLTR1BRD4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449785-A | Fungicides with triazole groups | HOFFMANN-LA ROCHE INC. (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0524439-A1 | Novel cyclohexane and tetrahydropyran derivatives and antifungal compositions containing these derivatives | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1993-01-27 | — | — | EP | disclosed |