Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871286 | 0.86 | KDM4E (0.41) | KDM4EGAAALDH1A1TDP1RAB9A | |
| SCHEMBL9241824 | 0.81 | MAPT (0.54) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL9245105 | 0.80 | MEN1 (0.35) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL9240813 | 0.78 | SIGMAR1 (0.53) | ALDH1A1RAB9ACYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL9238134 | 0.76 | ATM (0.51) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL9241807 | 0.73 | GAA (0.38) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL9244927 | 0.73 | DRD2 (0.40) | KDM4EGAAALDH1A1KMT2ATSHR | |
| SCHEMBL9241135 | 0.73 | HRH2 (0.43) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL19562044 | 0.71 | MAP4K1 (0.54) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL9551175 | 0.71 | SIGMAR1 (0.45) | MEN1KMT2AMAPTHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278890-B1 | Non-staining and slightly-staining antiozonants | GOODYEAR TIRE & RUBBER (US) | 1995-05-24 | — | — | EP | claimed |
| EP-0278890-B1 | Non-staining and slightly-staining antiozonants | GOODYEAR TIRE & RUBBER (US) | 1995-05-24 | — | — | EP | disclosed |
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |