Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9244924 | 1.00 | BCAT2 (0.40) | BCAT2MEN1KMT2ASMN1; SMN2HDAC4 | |
| SCHEMBL9249226 | 0.85 | RXRA (0.34) | BCAT2MEN1KMT2ASMN1; SMN2HDAC4 | |
| SCHEMBL9249216 | 0.85 | RXRA (0.34) | BCAT2MEN1KMT2ASMN1; SMN2HDAC4 | |
| SCHEMBL13674402 | 0.78 | TACR1 (0.33) | BCAT2MEN1KMT2ASMN1; SMN2HDAC4 | |
| SCHEMBL28602884 | 0.76 | BCAT2 (0.44) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL5163372 | 0.74 | CES1 (0.50) | BCAT2MEN1KMT2ASMN1; SMN2HDAC4 | |
| SCHEMBL30805663 | 0.73 | BCAT2 (0.42) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL4412147 | 0.73 | CES1 (0.48) | TSHRRECQLALDH1A1HSD17B10 | |
| SCHEMBL9472924 | 0.73 | BCAT2 (0.53) | BCAT2MEN1KMT2ASMN1; SMN2HDAC4 | |
| SCHEMBL9249909 | 0.72 | RXRA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588915-A4 | AZULENIC RETINOID COMPOUNDS, COMPOSITIONS AND METHODS. | UNIV HAWAII (US) | 1995-05-31 | — | — | EP | disclosed |
| EP-0588915-A1 | AZULENIC RETINOID COMPOUNDS, COMPOSITIONS AND METHODS | UNIVERSITY OF HAWAII (US) | 1994-03-30 | — | — | EP | disclosed |
| US-5235076-A | Anticarcinogenic agents | UNIVERSITY OF HAWAII (US) | 1993-08-10 | — | — | US | disclosed |
| WO-1992021643-A1 | AZULENIC RETINOID COMPOUNDS, COMPOSITIONS AND METHODS | UNIVERSITY OF HAWAII (US) | 1992-12-10 | — | — | WO | disclosed |