Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9249915 | 1.00 | RXRA (0.31) | RXRAPPARGCTSLCTSBCTSS | |
| SCHEMBL9249216 | 0.83 | RXRA (0.34) | RXRAPPARG | |
| SCHEMBL9249226 | 0.83 | RXRA (0.34) | RXRAPPARG | |
| SCHEMBL9244918 | 0.72 | BCAT2 (0.40) | — | |
| SCHEMBL9244924 | 0.72 | BCAT2 (0.40) | — | |
| SCHEMBL9247720 | 0.72 | BACE1 (0.34) | — | |
| SCHEMBL9425898 | 0.72 | BACE1 (0.34) | — | |
| SCHEMBL13674402 | 0.69 | TACR1 (0.33) | — | |
| SCHEMBL12510595 | 0.66 | RXRA (0.34) | RXRAPPARG | |
| SCHEMBL28602884 | 0.65 | BCAT2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588915-A4 | AZULENIC RETINOID COMPOUNDS, COMPOSITIONS AND METHODS. | UNIV HAWAII (US) | 1995-05-31 | — | — | EP | disclosed |
| EP-0588915-A1 | AZULENIC RETINOID COMPOUNDS, COMPOSITIONS AND METHODS | UNIVERSITY OF HAWAII (US) | 1994-03-30 | — | — | EP | disclosed |
| US-5235076-A | Anticarcinogenic agents | UNIVERSITY OF HAWAII (US) | 1993-08-10 | — | — | US | disclosed |
| WO-1992021643-A1 | AZULENIC RETINOID COMPOUNDS, COMPOSITIONS AND METHODS | UNIVERSITY OF HAWAII (US) | 1992-12-10 | — | — | WO | disclosed |