Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 14/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5532392 | 0.93 | THRB (0.37) | THRBTHRAMEN1ALDH1A1CYP1A2 | |
| Aziridine SCHEMBL11905310 | 0.89 | THRB (0.33) | THRBTHRAITGB3ITGA2BMEN1 | |
| Propane SCHEMBL1998876 | 0.82 | THRB (0.40) | THRBTHRAALDH1A1CYP1A2 | |
| SCHEMBL2704549 | 0.82 | — | — | |
| SCHEMBL30190455 | 0.81 | THRB (0.36) | THRBTHRAALDH1A1 | |
| SCHEMBL181262 | 0.81 | THRB (0.36) | THRBTHRAALDH1A1 | |
| SCHEMBL673452 | 0.78 | THRB (0.33) | THRBTHRAALDH1A1CYP1A2 | |
| SCHEMBL1535860 | 0.78 | THRB (0.35) | THRBTHRAALDH1A1CYP1A2 | |
| SCHEMBL18154865 | 0.78 | THRB (0.35) | THRBTHRAALDH1A1CYP1A2 | |
| SCHEMBL6899904 | 0.77 | THRB (0.34) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508576-B1 | Microcapsules from polyfunctional aziridines | MINNESOTA MINING & MFG (US) | 1995-07-19 | — | — | EP | disclosed |
| US-5401505-A | Microcapsules from polyfunctional aziridines | MINNESOTA MINING AND MANUFACTURING (US) | 1995-03-28 | — | — | US | disclosed |
| US-5169632-A | MICROCAPSULES FROM POLYFUNCTIONAL AZIRIDINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0508576-A1 | Microcapsules from polyfunctional aziridines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-10-14 | — | — | EP | disclosed |