SCHEMBL9245145

SCHEMBL9245145

Cc1cc(Oc2ccc(Cl)c3c2CCCC3)c(Cl)cc1NC(=O)NC(=O)c1ccccc1Cl.Cc1cc(Oc2ccc(Cl)c3c2CCCC3)c(Cl)cc1NC(=O)NC(=O)c1ccccc1F

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PYGL P06737 7/20 0.46
KMT2A Q03164 3/20 0.44
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
GCGR P47871 1/20 0.43
RAB9A P51151 4/20 0.42
NPC1 O15118 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
LMNA P02545 2/20 0.41
MEN1 O00255 1/20 0.41
RXFP1 Q9HBX9 1/20 0.40
PNLIP P16233 1/20 0.39
IDO1 P14902 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
POLB P06746 1/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8657063 0.97 KMT2A (0.46) PYGLKMT2AKDM4EALDH1A1GCGR
SCHEMBL8657275 0.95 PYGL (0.51) PYGLKMT2AALDH1A1GCGRRAB9A
SCHEMBL10961383 0.89 PYGL (0.51) PYGLKMT2AALDH1A1GCGRRAB9A
SCHEMBL8657436 0.87 KMT2A (0.50) PYGLKMT2AKDM4EALDH1A1RAB9A
SCHEMBL10772547 0.85 ALDH1A1 (0.50) PYGLKMT2AKDM4EALDH1A1RAB9A
SCHEMBL10964570 0.81 GCGR (0.55) PYGLKMT2AGCGRRAB9ANPC1
SCHEMBL11029367 0.79 PYGL (0.48) PYGLKMT2AALDH1A1GCGRRAB9A
SCHEMBL10959798 0.79 GCGR (0.50) PYGLKMT2AGCGRRAB9ANPC1
SCHEMBL8660767 0.79 POLB (0.41) KMT2AKDM4EALDH1A1RAB9ANPC1
SCHEMBL10961025 0.77 GCGR (0.51) PYGLKMT2AGCGRRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5420163-A Insecticides or miticides CIBA-GEIGY (US) 1995-05-30 US disclosed