Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9246659 | 0.91 | GRM2 (0.38) | PTGESGRM2EGLN1CHRNB2CHRNA2 | |
| SCHEMBL9246397 | 0.88 | CHRNB2 (0.32) | PTGESEGLN1CHRNB2CHRNA2CHRNB4 | |
| SCHEMBL9245509 | 0.87 | FFAR1 (0.33) | MCHR1 | |
| SCHEMBL9250091 | 0.86 | GRM5 (0.42) | PTGESEGLN1CHRNB2CHRNA2CHRNB4 | |
| SCHEMBL9245099 | 0.86 | MCHR1 (0.41) | PTGESEGLN1CHRNB2CHRNA2CHRNB4 | |
| SCHEMBL9249257 | 0.85 | PTGES (0.38) | PTGESGRM2EGLN1KMOBACE1 | |
| SCHEMBL9249265 | 0.85 | PTGES (0.38) | PTGESGRM2EGLN1KMOBACE1 | |
| SCHEMBL9244989 | 0.85 | PTGES (0.36) | PTGESGRM2EGLN1KMOBACE1 | |
| SCHEMBL9244993 | 0.85 | PTGES (0.36) | PTGESGRM2EGLN1KMOBACE1 | |
| SCHEMBL9244982 | 0.85 | PTGES (0.36) | PTGESGRM2EGLN1KMOBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447657-A | Liquid crystal compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-09-05 | — | — | US | disclosed |