Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 8/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9245099 | 0.89 | MCHR1 (0.41) | GRM5EGLN1PTGESCHRNB2CHRNA2 | |
| SCHEMBL9246659 | 0.89 | GRM2 (0.38) | GRM5EGLN1PTGESCHRNB2CHRNA2 | |
| SCHEMBL9247860 | 0.87 | CHRNB2 (0.33) | GRM5EGLN1CHRNB2CHRNA2CHRNB4 | |
| SCHEMBL9245765 | 0.86 | FFAR1 (0.38) | — | |
| SCHEMBL9245211 | 0.86 | PTGES (0.37) | GRM5EGLN1PTGESCHRNB2CHRNA2 | |
| SCHEMBL9245001 | 0.85 | GRM5 (0.46) | GRM5EGLN1PTGESAURKAABL1 | |
| SCHEMBL9245011 | 0.85 | GRM5 (0.46) | GRM5EGLN1PTGESAURKAABL1 | |
| SCHEMBL9241425 | 0.83 | GRM5 (0.45) | GRM5EGLN1PTGESAURKAABL1 | |
| SCHEMBL9241419 | 0.83 | GRM5 (0.45) | GRM5EGLN1PTGESAURKAABL1 | |
| SCHEMBL9246583 | 0.83 | GRM5 (0.45) | GRM5EGLN1PTGESAURKAABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447657-A | Liquid crystal compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-09-05 | — | — | US | disclosed |