SCHEMBL9247356

SCHEMBL9247356

CCCCCCCC(Cl)C(Cl)(Br)C(F)(F)Br

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
LCK P06239 1/20 0.34
PPARD Q03181 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
DNM1 Q05193 2/20 0.33
OPRM1 P35372 1/20 0.32
TSHR P16473 1/20 0.32
THRB P10828 1/20 0.32
FDPS P14324 2/20 0.32
ZDHHC7 Q9NXF8 1/20 0.32
FAAH O00519 4/20 0.31
CES1 P23141 3/20 0.31
GPR84 Q9NQS5 2/20 0.31
CES2 O00748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10519959 0.82 LMNA (0.35) LMNALCKPPARDZDHHC20ZDHHC2
SCHEMBL1961203 0.81 LMNA (0.38) LMNAMAPTDNM1OPRM1TSHR
SCHEMBL28332620 0.81 LMNA (0.38) LMNAMAPTDNM1OPRM1TSHR
SCHEMBL27326152 0.81 LMNA (0.38) LMNAMAPTDNM1OPRM1TSHR
SCHEMBL7856018 0.79 LMNA (0.39) LMNAMAPTDNM1OPRM1TSHR
SCHEMBL7096584 0.76 LMNA (0.41) LMNAMAPTDNM1OPRM1TSHR
SCHEMBL686672 0.76 LMNA (0.41) LMNAMAPTDNM1OPRM1TSHR
SCHEMBL10395459 0.76 LMNA (0.41) LMNAMAPTDNM1OPRM1TSHR
SCHEMBL27869201 0.76 LMNA (0.41) LMNAMAPTDNM1OPRM1TSHR
SCHEMBL10394692 0.74 MAPT (0.33) LMNAMAPTDNM1OPRM1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0320145-B1 Process for the production of olefin polymerisation catalysts SHELL OIL CO (US) 1995-05-17 EP disclosed
EP-0320150-B1 Propylene polymers and their production SHELL OIL CO (US) 1995-05-17 EP disclosed
US-5405737-A Silver halide color photographic light-sensitive material comprising blue sensitive emulsion layers containing acylacetoamide type yellow dye forming couplers and reduction sensitized silver halide emulsion FUJI PHOTO FILM CO., LTD. (JP) 1995-04-11 US disclosed
CN-1019496-B PROPOLENE POLYMER AND THEIR PRODUETION SHELL OIL CO (US) 1992-12-16 CN disclosed
US-4952480-A CATIONIC INDOLE CYANINE DYES HAVING A BORON ANION; PHOTOSENSITIVITY IN THE VISIBLE AND LONGER WAVELENGTHS; PLANOGRAPHY; PHOTORESISTS; COPYING FUJI PHOTO FILM CO., LTD. (JP) 1990-08-28 US disclosed
US-4870040-A Olefin polymerization catalysts from soluble magnesium alkoxides made from alkyl or aryl magnesium mixed with a branched or aromatic aldehyde SHELL OIL COMPANY (US) 1989-09-26 US disclosed
US-4870039-A Olefin polymerization catalysts from soluble magnesium alkoxides made from mixed magnesium alkyls and aryls SHELL OIL COMPANY (US) 1989-09-26 US disclosed
CN-1034210-A Olefin polymerization catalysis SHELL OIL CO (US) 1989-07-26 CN disclosed
CN-1033813-A Propene polymer and production thereof SHELL OIL CO (US) 1989-07-12 CN disclosed
EP-0320145-A2 Process for the production of olefin polymerisation catalysts SHELL OIL COMPANY (US) 1989-06-14 EP disclosed
EP-0320150-A2 Propylene polymers and their production SHELL OIL COMPANY (US) 1989-06-14 EP disclosed